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陶伟
邮  箱: weitao(AT)pku.edu.cn
职  称:
教授
个人简历
科研领域描述
主要研究方向:
1.基因表达的表观遗传调控机理
2.细胞衰老的表观遗传编程  
3.利用同卵双胞胎分析引起心脏疾病的表观遗传控制  
代表性论文
1. Zeng Y, Cheng L, Zhao L, Tan Q, Feng Q, Chen H, Shen K, Li J, Zhang F, Cao H, Gregory SG, Yang Z, Gu J, Tao W, Tian XL, Hauser ER , nteractions between Social/ behavioral factors and ADRB2 genotypes may be associated with health at advanced ages in China , BMC Geriatrics , 2013 , [Epub ahead of print]  
2. Luo M, Ling T, Xie W, Sun H, Zhu QY, Shen M, Zong L, Zhao Y, Gu J, Tao W*, Lu Z*, Grummt I*. , NuRD blocks reprogramming of mouse somatic cells into pluripotent stem cells. , Stem Cells , 2013 , 2013, 31:1278-1286  
3. Shen M, Zhou T, Zong L, Ling T, Lv GL, Zhang FX, Tao W* , The chromatin remodeling factor CSB recruits histone acetyltransferase PCAF to rRNA gene promoters in active state for transcription Initiation , PLoS ONE , 2013 , 2013, 8(5): e62668  
4. Ling T, Xie W, Luo M, Shen M, Zhu Q, Zong L, Zhou T, Gu J, Lu Z, Zhang F, Tao W* , CHD4 maintains demethylation state of rDNA promoters through inhibiting the expression of the rDNA methyltransferase recruiter TIP5 , Biochem Biophys Res Commun , 2013 , 19:101-107  
5. Xie W, Ling T, Zhou Y, Feng W, Zhu Q, Stunnenberg HG, Grummt I*, Tao W* , The chromatin remodeling complex NuRD establishes the poised state of rRNA genes characterized by bivalent histone modifications and altered nucleosome positions , PNAS , 2012 , 109:8161-8166  
6. Li Y, Tian T, Zong L, Tao W*, Liang QJ*. , Methylation of histone H3 lysine 9 and H3 lysine 27 during X chromosome inactivation in cancer cells , Chromosome Research , 2012 , 2:769-774  
7. Fu W*, Tao W*, Zheng PW, Fu JY, Bian ML, Jiang Q, Clarke PR and Zhang CM , Clathrin recruits phosphorylated TACC3 to spindle poles for bipolar spindle assembly and chromosome alignment , J Cell Sci , 2010 , 123: 3645-3651  
8. Sha Meng, Min Luo,He Sun, Xin Yu,Meili Shen,Quancang Zhang, Rudan Zhou, Wei Tao, Hongkui Deng and Zhigang Lu , Identification and characterization of bmi-1-responding element within the human p16 promoter , J Biol Chem , 2010 , 285: 33219-33229  
9. Alena Rego, Paul B. Sinclair, Wei Tao, Igor Kireev, and Andrew S. Belmont , The facultative heterochromatin of the inactive X chromosome has a distinctive condensed ultrastructure , J Cell Sci , 2008 , 121: 1119-1127  
10. A J. Albee, Wei Tao, and Christiane Wiese , Phosphorylation of maskin by Aurora-A is regulated by RanGTP and importin , J. Biol. Chem , 2006 , 15;281(50):38293-301  
11. Brien LL, Albee AJ, Liu LL, Tao W,Dobrzyn P, Lizarraga SB, Wiese C , The Xenopus TACC homologue, maskin, functions in mitotic spindle assembly , Molecular Biology of the Cell , 2005 , 16 (6): 2836-2847  
12. Cai N., Hu K., Tao W., Su W., Li F., Hu Y. S , Structural model of nucleolar DNA in situ in Allium sativum cells revealed by image processing. , Prog Biochem Biophys. , 2004 , 31, 432-437  
13. He J., Tao W. and Hao S. , Ultrastructural localization of transcription sites of rRNA genes in the nucleolus of Wheat , Acta Biologiae Experimentalis Sinica. , 2004 , 35,71-75  
14. Tao W, Huang BQ, Liu CX and Zhai ZH , In situ visualization of rDNA arrangement and its relationship with subnucleolar structural regions in cell nucleolus , J Cell Sci , 2003 , 116 (6): 1117-1125  
15. Zhao Y, Lu ZG, Wu M, Tao W, Zhai ZH , Effects of phosphocreatine on apoptosis in a cell-free system , J Biol Chem , 2001 , 276: 34573-34578  
16. Tao W, Yan CH, Cai T, Hao S, Zhai ZH , Structural components of nuclear body , Cell Research , 2001 , 11(1): 68-73  
17. Tao W, He J, He MY, Hao S , Ultrastructural localization of active genes in nucleus , Chinese Science Bulletin , 2001 , 46(11): 925-930  
18. Tao W, Zhang LY, Huang BQ, He MY, and Hao S , The structural transformation of nucleolar DNA and its arrangement in nucleolus of HeLa cells , Acta Botanica Sinica , 2001 , 43 (1): 6-11  
19. Zhao Y, Liu XL, Wu M, Tao W, Zhai ZH , In vitro nuclear reconstitution could be induced in a plant cell-free system , FEBS Letters , 2001 , 80 : 208-212  
20. Tao W, Jiao MD, He J, Hao S , The configuration of nucleolar DNA in situ in Allium cepa cells , Chinese Science Bulletin , 2001 , 46(1): 62-67  
21. Liu X., Tao W., Gao Y., Zhai Z. , The reconstitution of nuclesome in cell-free system. , Acta Botanica Sinica. , 2001 , 43, 356-362  
22. Yang W., Zhang L., Lu Z., Tao W., Zhai Z. , A new method for protein coexpression in Escherichia coli using two incompatible plasmids. , Protein Expression and Purification. , 2001 , 22, 472-478  
23. Bi X., Jiao M., Tao W., Huang B. , Distribution of DNA and localization of rRNA transcription in G2 phase nucleolus of Physarum polycephalum. , Progress in Natural Science. , 2001 , 8,631-636  
24. Lu Z., Yang W., Cao Q., Tao W., Zhai Z. , Identification of inhibitor of apoptosis specific DNase in Xenopus egg extract . , Chinese Science Bulletin. , 2001 , 46, 1449-1454  
25. Bi XH, Jiao MD, Tao W, Huang BQ , Distribution of DNA and localization of rRNA transcription in G2 phase nucleolus of Physarum polycephalum , Prog Nat Sci , 2000 , 8: 631-636  
26. Tao W, Jiao MD, He J, Hao S , Structure of nucleolus and transcription sites of nucleolar DNA in rat liver cells , Science in China (Series C) , 2000 , 43(3):302-309  
27. Tao W., Liu X., Zhao Y., Lu Z., Zhai Z. , Observation of chromosome structure by means of electron microscopy. , Acta Scientiarum Naturalium University Pekinensis. , 2000 , 36,795-801  
28. Zeng XL, Xing M, Jiao MD, Tao W, Hao S , Actin is localized in the nucleolar skeleton of Physarum polycephalum , Acta Botanica Sinica , 1999 , 41 (1): 6-12  
29. Tao W., Duan X., He M. and Hao S. , Immuno-cytochemical localization of myosin in barly nuclear matrix and chromosomal scaffold. , Acta Biologiae experimentalis Sinica. , 1998 , 31,96-103
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