北京大学 | ENGLISH
师资力量
按拼音排序【正、副高职称】
当前位置: 师资力量 > 在职教师 > 按拼音排序
陈建国
邮  箱: chenjg(AT)pku.edu.cn
职  称:
教授
办公室地址: 北京市海淀区颐和园路5号,北京大学,金光生命科学大楼,100871
实验室地址: 北京市海淀区颐和园路5号,北京大学,金光生命科学大楼,100871
个人简历
教育经历
1982 - 1985  研究生  浙江农业大学
1989 - 1994  研究生  北京大学生命科学学院
1997 - 1999  交换学生 东京大学医学部
工作经历
1999 - 至今 , 教授 , 北京大学生命科学学院
1999 - 2000 , 访问学者 , 香港科技大学生物学系
1997 - 1999 , 访问学者 , 东京大学医学部
1994 - 1999 , 副教授 , 北京大学生命科学学院
1985 - 1989 , 讲师 , 浙江农业大学生物技术中心
社会服务工作
实验动物中心 主任 , 北京大学
北京大学前沿交叉学科研究院 学术委员会委员
荣誉奖励
国家级教学成果奖二等奖 , 2005
北京市级高等教育教学成果奖一等奖 , 2004
全国高校精品课(细胞生物学) , 2003
北京市级高等教育教学成果奖二等奖 , 2001
北京市级高等教育教学成果奖二等奖 , 1997
国家杰出青年科学基金 , 1995
杂志编辑
编委 , 北京大学学报 (中国) , 2005 - 至今
科研领域描述
本实验室主要兴趣在于:
  细胞骨架的分子生物学
  神经系统的发育及细胞分化
  细胞内膜系统

代表性论文
1. Zhou Haining, Tianning Wang, Tao Zheng, Junlin Teng, Jianguo Chen. Cep57 is a Mis12-interacting kinetochore protein involved in kinetochore targeting of Mad1-Mad2. Nature Communications, 2016. 7, doi:10.1038/ncomms10151
2. Chen Liang, Sizheng Xu, Yiwei Xu,Weiwei Lu, Lin Liu, Di Yue, Junlin Teng* & Jianguo Chen , Cab45S Promotes Cell Proliferation throughSERCA2b Inhibition and Ca2+ Signaling , Oncogene , 2016 , 35: 35-46
3. Lv Kaosheng, Liang Chen, Yuanjun Li, Pengli Zheng, Yingying Liu, Zenglong Li, Jianguo Chen, and Junlin Teng , Trip6 Promotes Dendritic Morphogenesis through Dephosphorylated GRIP1-dependent Myosin VI and F-actin Organization , J. Neurosci. , 2015 , 35(6):2559-2571  
4. Chen L, Xu S, Liu L, Wen X, Xu Y, Chen J* and Teng J* , Cab45S inhibits the ER stress-induced IRE1-JNK pathway and apoptosis via GRP78/BiP , Cell Death Dis. , 2014 , (2014)5:e1219 , [Full Text]  
5. Qiao Wang, Birong Shen, Liang Chen, Pengli Zheng, Hui Feng, Qingsong Hao, Lin Liu, Xiao Liu, Sizheng Xu, Jianguo Chen*, and Junlin Teng* , Extracellular Calumenin Suppresses ERK1/2 Signaling and Cell Migration by Protecting Fibulin-1 from MMP-13-mediated Proteolysis , Oncogene , 2014 , doi: 10.1038/onc.2014.52 (online) , [Full Text]  
6. Wang Jingjing, Shan Chunyan, Cao Wenyuan, Zhang Chen, Teng Junlin, Chen Jianguo , SCG10 promotes non-amyloidogenic processing of amyloid precursor protein by facilitating its trafficking to the cell surface , Human Molecular Genetics , 2013 , 22(24): 4888-4900. , [Full Text]  
7. Hui Feng, Liang chen, Qiao Wang, Birong Shen, Lin Liu, Pengli Zheng, Sizheng Xu, Xiao Liu, and Jianguo Chen, Junlin Teng , Calumenin-15 Facilitates Filopodia Formation by Promoting TGF-β Superfamily Cytokine GDF-15 TranscrIption , Cell Death and Disease , 2013 , 4, e870; doi:10.1038/cddis.2013.403 , [Full Text]  
8. He Runsheng, Wu Qixi, Zhou Haining, Huang Ning, Chen Jianguo*, Teng Junlin* , Cep57 is required for cytokinesis by facilitating central spindle microtubule organization. , J. Biol. Chem. , 2013 , 288(20): 14384-14390. , [Full Text]  
9. He Runsheng, Huang Ning, Bao Yitian, Zhou Haining, Teng Junlin, Chen Jianguo , LRRC45, A Novel Centrosome Linker Component, Is Required for Centrosome Cohesion. , Cell Reports , 2013 , 4: 1100-1107 , [Full Text]  
10. Qiao Wang, Birong Shen, Pengli Zheng, Hui Feng, Yige Guo, Wenyuan Cao, Liang Chen, Xiao Liu, Guodong Zhao, Sizheng Xu, Weide Shen, Jianguo Chen, and Junlin Teng , BmCREC Is an ER-resident Protein and Required for ER/Golgi Morphology , J. Biol. Chem. , 2013 , 288(37):26649-26657 , [Full Text]  
11. Jian Xue, Xiao-Qin Zhang, Hai-Jun Xu, Hai-Wei Fan, Hai-Jian Huang, Xiao-Fang Ma, Chun-Yan Wang, Jian-Guo Chen, Jia-An Cheng, Chuan-Xi Zhang , Molecular characterization of the flightin gene in the wing-dimorphic planthopper, Nilaparvata lugens, and its evolution in Pancrustacea , Insect Biochemistry and Molecular Biology , 2013 , 43(5):433-443 , [Full Text]  
12. Miao Linqing, Teng Junling , Lin Jiqiang, Liao Xianzhi, and Chen Jianguo , 14-3-3 protein interact with neurofilament protein-L (NF-L) and regulate dynamic assembly of neurofilament , J Cell Sci , 2013 , 126:427-436. , [Abstract]  
13. Wu Qixi, He Runsheng, Zhou Haining, Yu CH Albert, Zhang Bo, Teng Junlin and Chen Jianguo , Cep57, a NEDD1-binding pericentriolar material component, is essential for spindle pole integrity , Cell Res , 2012 , 22(9):1390-1401 , [Full Text]  
14. Liu Yingying, Lv Kaosheng, Li Zenglong, Yu CH Albert, Chen Jianguo and Teng Junlin , Pacsin1, a tau-interacting protein, regulates axonal elongation and branching by facilitating microtubule instability , J Biol. Chem , 2012 , 287(47):39911-39924. , [Full Text]  
15. Wang Qiao, Feng Hui, Zheng Pengli, Shen Birong, Chen Liang, Liu Lin, Liu Xiao,Hao Qingsong, Wang Shunchang, Chen Jianguo and Teng Junlin. , The Intracellular Transport and Secretion of Calumenin-1/2 in Living Cells , PloS One. , 2012 , 7(4):e35344.doi:10.1371/ journal.pone.0035344 , [Full Text]  
16. Ding NZ, He CQ, Hu JS, Teng J and Chen J , Yin Yang-1 Regulates the Characterized Murine Focal Adhesion-Associated Protein Promoter , DNA Cell Biol , 2011 , 31(4):496-503  
17. Yang CZ, Li HL, Zhou Y, Chai RC, Zhao R, Dong Y, Xu ZY, Lau LT, Yingge Z, Teng J, Chen J, Yu AC , A new specialization in astrocytes: Glutamate- and ammonia-induced nuclear size changes , J Neurosci. Res , 2011 , 89:2041–2051  
18. Wang Qiao, Birong Shen, Pengli Zheng, Hui Feng, Liang Chen, Jing Zhang, Chuan-Xi Zhang, Guozheng Zhang, Junlin Teng and Jianguo Chen. , Silkworm coatomers and their role in tube expansion of posterior silkgland , PLoS One , 2010 , 5(10):e13252 , [Full Text]  
19. Wu Z, Wang Q, Feng Q, Liu Y, Teng J, Yu AC, Chen J , Correlation of the virulence of CSFV with evolutionary patterns of E2 glycoprotein , Front Biosci. , 2010 , 2:204-20  
20. Chunbo Lou, Xili Liu, Ming Ni, Yiqi Huang, Qiushi Huang, Longwen Huang, Lingli Jiang, Dan Lu, Mingcong Wang, Chang Liu, Daizhuo Chen, Chongyi Chen, Xiaoyue Chen, Le Yang1,2, Haisu Ma, Jianguo Chen & Qi Ouyang , Synthesizing a novel genetic sequential logic circuit: a push-on push-off switch , Molecular Systems Biology , 2010 , 6: Article number 350; doi:10.1038/msb.2010.2  
21. Wang Qiao, Teng Junlin, Shen Birong, Zhang Wei, Guo Yige, Su Xiaolei,Zhang Chuanxi, Yu Albert CH, Chen Jianguo. , Characterization of Kinesin-like Proteins in Silkworm Posterior Silkgland Cells , Cell Res. , 2010 , 20: 713-727  
22. Yan Dong, Hua Dong Liu, Rui Zhao, Chun Zhang Yang, Xiao Qian Chen, Xin HongWang, Lok Ting Lau, Jianguo Chen and Albert Cheung Hoi Yu , Ischemia activates JNK/c-Jun/AP-1 pathway to up-regulate 14-3-3gamma in astrocyte , J Neurochem , 2009 , 109 (Suppl. 1) :182–188  
23. Hu Jinsong, Teng Junlin, Ding Naizheng, He Mei, Yuhui Sun, Albert Cheung Hoi Yu, Chen Jianguo , FAAP, a novel murine protein, is involved in cell adhesion through regulating vinculin-paxillin association , Frontiers in Bioscience , 2008 , 13: 7123-7131  
24. Ge Jun-Qing, Zhang-Nv Yang, Xu-Dong Tang, Hai-Jun Xu, Jian Hong, Jian-Guo Chen and Chuan-Xi Zhang , Characterization of a nucleopolyhedrovirus with a deletion of the baculovirus core gene Bm67 , J Gen Virol , 2008 , 89: 766-774  
25. Feng Qian, Yingying Liu, Xiuxia Liu, Hongkui Deng, Mingxiao Ding, Albert C H Yu and Jianguo Chen , Baculovirus surface display of SARS Coronavirus (SARS-CoV) spike protein and immunogenicity of the displayed protein in mice model , DNA and Cell Biology. , 2006 , 25(12): 668-673  
26. Huihui Li, Yan Guo, Junlin Teng, Mingxiao Ding, Albert Cheung Hoi Yu and Jianguo Chen , 14-3-3gamma affects dynamics and integrity of glial filaments by binding to phosphorylated GFAP , J. of Cell Science. , 2006 , 119: 4452-4461  
27. Keqiang Fan, Ping Wei, Qian Feng, Sidi Chen, Changkang Huang, Liang Ma, Bing Lai, Jianfeng Pei, Ying Liu, Jianguo Chen, and Luhua Lai , Biosynthesis, Purification, and Substrate Specificity of Severe Acute Respiratory Syndrome Coronavirus 3C-like Proteinase. , J. of Biological Chemistry. , 2004 , 279(3): 1637–1642  
28. Qian Feng, Huan Yu, Yingying Liu, Chengqiang He, Jingsong Hu, Huachun Sang, Neizheng Ding, Mingxiao Ding, Yin-Wan Wendy Fungc, Lok-Ting Lauc, Albert Cheung-Hoi Yuc, Jianguo Chen , Genome comparison of a novel foot-and-mouth disease virus with other FMDV strains , BBRC , 2004 , 323:254-263  
29. Chen XQ, Chen JG, Zhang Y, Hsiao WW and Yu AC , 14-3-3gamma Is upregulated by in vitro ischemia and binds to protein kinase Raf in primary cultures of astrocytes. , Glia , 2003 , 42(4):315-24  
30. Feng Qian, Xi Chen, Ou Ma, Yingying Liu, Mingxiao Ding, ,Richard A. Collins, Lung-Sang Ko, Jun Xing, Lok-Ting Lau, , Albert Cheung Hoi. Yu and Jianguo Chen , Serotype and VP1 Gene Sequence of a Foot-and-Mouth Disease Virus from Hong Kong , BBRC , 2003 , 302(4):715-721  
31. Chen Xi , Qian Feng, Zhiyin Wu, Yingying Liu, Kun Huang, Rui Shi, Sidi Chen, Wen Lu, Mingxiao Ding, Richard A. Collins, Albert Cheung-Hoi Yu and Jianguo Chen , RNA-dependant RNA Polymerase Gene Sequence from Foot-and Mouth Disease Virus in Hong Kong , BBRC , 2003 , 308:899-905  
32. Sang huaceng, Zhonghua Lu, Yulong Li, Binggen Ru, Wenqing Wang, and Jianguo Chen , Phosohorylation of GSK-3 beta in intact cells influences the stability of microtubules , Neuroscience Leter , 2003 , 312:141-144  
33. Chengrong Lu, Yong Li, Yanlin Zhao, Guichun Xing, Fei Tang, Qingming Wang,Yuhui Sun, Handong Wei, Xiaoming Yang, Chutse Wu, Jianguo Chen, Kun-liang Guan, Chenggang Zhang, Huipeng Chen, Fuchu He. , Intracrine hepatopoietin potentiates AP-1 activity through JAB1 independent of MAPK pathway. , The FASEB J. , 2002 , 16: 90-92  
34. Guo Yan, Chaolaing Wei, Jinsong Hu and Jianguo Chen , Fibrillarin redistributes to the spindle poles and partially colocalizes with NuMA during mitosis , Chinese Science Bulletin , 2002 , 47:1995-1998  
35. TengJ unlin, Yosuke Takei, Akihiro Harada, Takao Nakata, Jianguo Chen and Nobutaka Hirokawa , Synergistic effects of MAP2 and MAP1B knockout in neuronal migration, dendritic outgrowth, and microtubule organization. , J. Cell Biology. , 2001 , 155: 65-76.  
36. Pan Ning and Jianguo Chen , NF-L and NF-M are expressed in epithelial cells and coassemble with keratin and vimentin , Chinese Science Bulletin , 2000 , 46(4):310-312  
37. Chen, J., Nakata, T., Zhang, Z. and Hirokawa, N , The C-terminal tail domain of neurofilament protein-H (NF-H) forms the crossbridges and regulates neurofilament bundle formation , J. of Cell Science. , 2000 , 113: 3861-3869  
38. Yang Xiaoyong, Junlin Teng, Yang Jin and Jianguo Chen , MAP2c confers drug stability to microtubules in vivo , Chinese Science Bulletin , 1999 , 44(23):2162-2167  
39. Terunaga Nakagawa, Jianguo Chen, Zhizeng Zhang, Yoshimitsu Kanai, and Nobutaka Hirokawa , Two Distinct Function of the Carboxyl-terminal Tail Domain of NF-M upon Neurofilament Assembly: Cross-bridge Formation and Longitudinal Elongation of Filaments , J. Cell Biol., , 1995 , 129:411-429.  
40. Kanai Y., Chen J. and Hirokawa N. , Microtubule bundling by tau proteins in vivo: analysis of functional domains , EMBO J , 1992 , 11, 3953 - 3961  
41. Chen, J., Kanai, Y., Cowan, N. J. and Hirokawa, N. , Projection domains of MAP2 and tau determine spacings between microtubules in dendrites and axons , Nature. , 1992 , 360, 674 - 677.
执教课程
细胞生物学 , 主持人 , 北京大学 , 1994-2013 秋季学期
实验室简介
[友情链接]
北大生科微信公众号 生声不息微信公众号
联系我们 | 地理位置
北京大学生命科学学院 版权所有 地址:北京市海淀区颐和园路5号金光生命科学大楼