简体中文

Message from the Dean

Biology is one of the oldest disciplines at PKU, which originated from the Imperial University of Peking (founded in 1898), the first national comprehensive university in China.

details >

Research News MORE>>

Single-Cell RNA-Seq Reveals Dynamic Early Embryonic-like Programs during Chemical Reprogramming

Jun 22，2018

Highly efficient chemical reprogramming enables single-cell transcriptomic analysis scRNA-seq reconstructs reprogramming trajectories and major molecular events An early embryonic-like gene network and epigenetic status drive CiPSC generation Chemical reprogramming is accelerated by enhancing the 2C-like program

The Arabidopsis USL1 controls multiple aspects of development by affecting late endosome morphology

Jun 19，2018

The polar transport of auxin controls many aspects of plant development. However, the molecular mechanisms underlying auxin tranport regulation remain to be further elucidated. We identified a mutant named as usl1 (unflattened and small leaves) in a genetic screen in Arabidopsis thaliana. The usl1 ...

Cryo-EM structure of human mitochondrial trifunctional protein

Jun 19，2018

The β-oxidation is a fundamental metabolic pathway that breaks down fatty acid molecules to generate energy. The mitochondrial trifunctional protein (TFP) catalyzes three reactions during this process, and mutations in the TFP subunits cause diseases such as mitochondrial trifunctional protein defi...

Single-cell multi-omics sequencing of human early embryos

Jun 19，2018

DNA methylation, chromatin states and their interrelationships represent critical epigenetic information, but these are largely unknown in human early embryos. Here, we apply single-cell chromatin overall omic-scale landscape sequencing (scCOOL-seq) to generate a genome-wide map of DNA methylation a...

lecture MORE>>

Jun
15

Molecular Mechanisms Underlying the Elaboration of Neural Connectivity

Speaker：Alex L. Kolodkin, Ph.D.

Time：13:00-14:30

Location：Youcai Deng Hall，School of Life Sciences

Jun
01

Epigenetic switching and antisense transcription

Speaker：Prof Caroline Dean

Time：13:00-14:30

Location：Youcai Deng Hall，School of Life Sciences

May
25

CRISPR-Cas Mediated Cleavage of Invading Nucleic Acids

Speaker：Yanli Wang, Ph.D.

Time：14:00-15:30

Location：Youcai Deng Hall，School of Life Sciences

May
18

Transforming Medical Care with Next Generation Tec...

Speaker：Kang Zhang, M.D., Ph.D.

Time：13:00-14:30

Location：Youcai Deng Hall，School of Life Sciences

about school

[Site]

[Lab]

LINKS