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Biology is one of the oldest disciplines at PKU, which originated from the Imperial University of Peking (founded in 1898), the first national comprehensive university in China.

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Research News MORE>>

Manganese Increases the Sensitivity of the cGAS-STING Pathway for Double-Stranded DNA and Is Required for the Host Defense against DNA Viruses

Apr 12，2018

•Mn2+ is released from organelles and accumulates in the cytosol upon virus infection •Mn2+ activates anti-viral innate immunity via the cGAS-STING pathway •Mn2+ increases the sensitivity of cGAS to dsDNA and promotes STING activation •Mn-deficient mice are more vulnerable to DNA viruses

The TIE1 transcriptional repressor controls shoot branching by directly repressing BRANCHED1 in Arabidopsis

Mar 29，2018

Shoot branching is a key factor that not only affects plant survival but also determines food productivity in crop species. BRANCHED1 (BRC1) integrates internal and external signals to determine shoot branching. However, the regulation of BRC1 at the protein level remains elusive. We found that TIE1...

Structure and evolution of the Fam20 kinases

Mar 24，2018

The Fam20 proteins are novel kinases that phosphorylate secreted proteins and proteoglycans. Fam20C phosphorylates hundreds of secreted proteins and is activated by the pseudokinase Fam20A. Fam20B phosphorylates a xylose residue to regulate proteoglycan synthesis. Despite these wide-ranging and impo...

A single-cell RNA-seq survey of the developmental landscape of the human prefrontal cortex

Mar 15，2018

The mammalian prefrontal cortex comprises a set of highly specialized brain areas containing billions of cells and serves as the centre of the highest-order cognitive functions, such as memory, cognitive ability, decision-making and social behaviour1,2. Although neural circuits are formed in the lat...

lecture MORE>>

Apr
27

Reverse-Engineer GOD’s Creations

Speaker：Tzumin Lee, M.D., Ph.D.

Time：13:00-14:30

Location：Youcai Deng Hall，School of Life Sciences

Apr
20

How the brain encodes time

Speaker：Paul H. Taghert, Ph.D.

Time：13:00-14:30

Location：Youcai Deng Hall，School of Life Sciences

Apr
13

3D Genome Organization & Transcription Regulation in Cancer Cells

Speaker：Yijun Ruan

Time：13:00-14:30

Location：Youcai Deng Hall，School of Life Sciences

Apr
06

Design and Development of New Therapies Using Chim...

Speaker：Xiuli Wang MD, PhD

Time：13:00-14:30

Location：Youcai Deng Hall，School of Life Sciences

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