北京大学 | ENGLISH
讲座信息
Molecular Mechanisms Underlying the Elaboration of Neural Connectivity
发布时间:2018-05-21      点击量:598
主讲人:Alex L. Kolodkin, Ph.D.
讲座地点:生命科学学院邓祐才报告厅
讲座日期:2018-06-15
讲座时间:13:00 — 14:30
 
生命科学学院2018年度春季学期学术系列讲座之十二
题目:Molecular Mechanisms Underlying the Elaboration of Neural Connectivity
讲座人:Alex L. Kolodkin, Ph.D.
Charles J. Homcy and Simeon G. Margolis Professor
Solomon H. Snyder Dept. of Neuroscience
Investigator, Howard Hughes Medical Institute
The Johns Hopkins School of Medicine
时间:2018年6月15日(星期五),13:00-14:30
地点:生命科学学院邓祐才报告厅
主持人:李毓龙研究员
摘要:
Neural connectivity and morphology are regulated by a wide range of extracellular and intracellular mechanisms during development and in the adult nervous system. We have recently investigated cues that regulate laminar organization of neural projections in both the vertebrate visual system and the Drosophila central brain. Further, it is becoming apparent that related guidance cues also regulate of synaptic plasticity. I will discuss our efforts to define signaling events that influence connectivity and plasticity, with a focus on semaphorin-mediated regulation of neural lamination and homeostatic plasticity.
Neural connectivity and morphology are regulated by a wide range of extracellular and intracellular mechanisms during development and in the adult nervous system. We have recently investigated cues that regulate laminar organization of neural projections in both the vertebrate visual system and the Drosophila central brain. Further, it is becoming apparent that related guidance cues also regulate of synaptic plasticity. I will discuss our efforts to define signaling events that influence connectivity and plasticity, with a focus on semaphorin-mediated regulation of neural lamination and homeostatic plasticity.
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